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The need for the cycle between methionine and homocysteine to function in a repetitive fashion is illustrated by the fact that in men the homocysteine moiety is recycled between methionine and homocysteine twice before being converted to cystathionine, but in women it is recycled about 1.5 times (Chiang)
Life Sci 2019
Wan X, Zhou X-R, Moncalian G, Su L, Chen W-C, Zhu H-Z, Chen D, Gong Y-M, Huang F-H, Deng Q-C
Multi-organ and sex-specific studies examining intestinal, hepatic, and neural Mn regulation will be essential to construct a systems-level model of Mn metabolism
& Stein, P
doi: 10.1016/S0006-291X(84)80190-4
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