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The claim traces back to studies showing that copper and zinc cations can inhibit 5-alpha reductase activity in isolated enzyme assays
Brain : J
Simpson, R
The largest change was seen for PE e 36:1 (log 2 = 4.55), highly enriched in Ms4a15 OE (log 2 = 2.91), indicating both properties (MUFA and vinyl ether) are adept at absorbing this reaction
doi: 10.1038/s41598-025-97054-8 25 KhongpiroonCBuakaewWBrindleyPJPotikanondSDaowtakKThongsriYet al
Response: We appreciate commenters' suggestions that we should focus on improving policies that directly help patients understand costs, and we may revisit the consumer-friendly display requirements in future rulemaking
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