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Understanding that your symptoms are rooted in real, physiological processeslike the breakdown of the carnitine shuttle and the failure of mitochondrial energy productioncan be incredibly validating

Irregular Menstrual Cycles & Fertility Having a higher BMI can contribute to having irregular cycles

RMD Open

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Classical apoptosis remains the dominant mode of follicular loss: double-strand breaks trigger ATM/ATR-p53 signalling, up-regulating BAX/BAK and prompting mitochondrial outer-membrane permeabilisation with cytochrome-c release [78,79,80,81]

Fudan University Oncology Hospital, 2008