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10.1016/s0278-6915(98)00008-8 [DOI] [PubMed] [Google Scholar] Jain, R

Additionally, studies in mice have demonstrated that -KG activates nuclear factor erythroid 2-related factor 2 (Nrf2) by activating the ERK signaling pathway in the endothelium of the thoracic aorta to counteract oxidative stress and mitochondrial impairment, thereby providing protective effects against endothelial damage induced by hyperlipidemia

The appetite suppression becomes less pronounced