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To test for the generality of spike effects on the BCi-NS1.1 epithelia we tested the two different spike protein variants on primary human bronchial epithelial (HBE) cells

These drugs should be used cautiously or avoided in patients with a history of pancreatitis, those with certain rare thyroid cancers (such as medullary thyroid carcinoma), patients with severe gastrointestinal disorders, and pregnant or breastfeeding women

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Notably, the lower ghrelin levels in PAR2-R38E mice were also associated with reduced postprandial GLP-1 levels (Figure 1H), emphasizing the role of ghrelin for postprandial GLP-1 secretion

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