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That insight supports an educated conversation with your provider, who determines any dosing decision individually

Moreover, given no heterogeneous treatment effects found by age, gender, or diabetes severity for GLP-1RAs versus insulin in our previous analyses [6] and limited study subjects with different patient characteristics in the present study, performing the cost-effectiveness analysis stratified by different patient demographic or clinical characteristics would be infeasible

These overlapping half-lives inform the washout question discussed in the next section