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Immune activation by microbiome shapes the colon mucosa: Comparison between healthy rat mucosa under conventional and germ-free conditions

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Interestingly, it also stimulates insulin secretion from -cells, but with much lower potency than GLP-1 with the mechanism potentially due to the weak binding of glucagon at GLP-1 receptor site [11]

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Lee RH, Mara Greenberg, Metz TD, Pettker CM