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Studies have shown significant effects on body weight, glucose metabolism, and overall metabolic function

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Design and synthesis of conformationally constrained glucagon-like peptide-1 derivatives with increased plasma stability and prolonged in vivo activity

The study, as reported in the New England Journal of Medicine, varied the dosages administered, noting the highest weight loss at the largest dosage

Conflicting resultsneed for more transparent and reproducible research

Whether that difference is clinically meaningful depends entirely on what your goals are and what you've already achieved