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Some of these changes went beyond what weight loss alone would explain, pointing to direct metabolic effects from the triple-agonist mechanism

1.Leehey DJ, Rahman MA, Borys E, Picken MM, Clise CE

The first GLP-1 receptor agonist that became available was semaglutide, explains Louis Aronne, MD , the Sanford I

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This treatment should be provided within specialist weight management services, is typically time-limited (generally up to 2 years), and must be part of a comprehensive programme including dietary modification, increased physical activity, and behavioural support