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Figure 1 2 Physiological mechanism of the dual GIP/GLP-1 receptor agonist on weight loss: Evidence from preclinical studies GLP-1 is a peptide that is synthesized by L cells of the intestine, and once GLP-1 is released, it binds to its receptor expressed in -cells, cells, the kidneys, the lungs, gastric mucosa, the heart, the brain, and immune cells (16)

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Kidney Int 1992;42:647656

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doi: 10.1016/j.cyto.2016.06.028