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Hypoxia stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase through accumulation of lanosterol and hypoxia-inducible factor-mediated induction of insigs

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For this purpose, 4 l of reagent B was preliminarily applied to the tube wall above the level of reagent A, and then the biomaterial (according to the SUM and NEO schemes) or trichloroacetic acid (according to schemes X and ST) was added, carefully pipetting, mixing, and rinsing the walls with a mixture of reagents

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