In a recent large cross-sectional study evaluating 9823 T2DM patients from around the world (including Brazil), 34.8% of patients had established cardiovascular disease (CVD), of whom 85.8% had atherosclerotic cardiovascular disease (ASCVD) [8]
With clinical confidence high, injectables are expected to remain a cornerstone even as new formats emerge
Patients should be educated to report severe or persistent abdominal pain, as tirzepatide has been associated with acute pancreatitis in clinical trials
It encodes a preproglucagon of 180 aa residues that contains glucagon, GLP-1, and GLP-2
Some people respond better to one than the other, which is why medical guidance matters
Both reduce appetite and may support weight management