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Most are taken via weekly or daily self-injection

ABR thresholds were determined 3 days post-treatment at various frequencies (4, 10, 20, and 40 kHz)

Text is machine generated and may contain inaccuracies

Semaglutide Semaglutide 2.4mg 68 14.9 17.4% Tirzepatide 2539 Tirzepatide 72 15 22.5% Liraglutide 3.0 mg Liraglutide 56 63.2% 5% 27.1% 25% GLP-1 4 GLP-1 L L GLP-1 L L L L GLP-1 L L L L GLP-1 L GLP-1 L 5 GLP-1 4 GLP-1 L GLP-1 (kg) 30 35 ml 2 3 BMR 7 9 GhrelinLeptin GLP-1 QA GLP-1 Q Q GLP-1 Q Q QGLP-1 Q QBMI BMI 30 kg/m BMI 27 30 kg/m 335 986 37 Top 15

Collaboration, E

The third term is the rate of production of oxidized GSSG from GSH via the enzyme GPX and the fourth term is the conversion of GSSG back to GSH via the enzyme GR