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Side effects may persist for several weeks during elimination, with blood glucose levels typically rising within one to two weeks of stopping

Pham VT, Fehlbaum S, Seifert N, et al

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Manufacturing scalability and reproducibility present further obstacles

The pathogenesis is thought to involve immune dysregulation from GLP-1 receptor agonism with delayed-type hypersensitivity, potentially enhanced by UV exposure in photodistributed areas