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Additional information on materials and methods can be found in the Supplementary Materials and Methods

Your brain's appetite control centers don't "learn" to stay suppressed without the medication present

The article describes ideal candidates as having stable thyroid hormone replacement, normal or near-normal TSH, and a clear metabolic reason for treatment such as prediabetes, type 2 diabetes, or weight management

If GLP-1 medications really do lower chronic inflammation, the benefits could extend far beyond weight loss

Vitamin B12 is not made by the body and is provided either by diet or supplementation

The BALANCE (Better Approaches to Lifestyle and Nutrition for Comprehensive hEalth) Model a CMS voluntary demonstration for both Medicare and Medicaid opened to state Medicaid agency participation beginning in May 2026