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Interestingly, while maternal PE MPs/NPs exposure increased umbilical flow by 43% in mice, it did not affect fetal growth or brain circulationsuggesting effective compensatory mechanisms (Hanrahan et al., 2024)

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Because collagen is hydrolyzed into small, bioavailable peptides, it enters the bloodstream relatively quickly, making it accessible during these peak recovery hours

However, the specific molecular mechanisms by which senescent macrophages induce VC remain unclear, and require further investigation