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It is asserted here that at low concentration, these products augment anti-tumour immunity by stimulating immune cells and at high concentration, result in immune suppression

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32 The primary outcome for the trial was the first occurrence of a major adverse cardiovascular event (death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke)

For biologics and their alternatives (biosimilars), price reductions tend to happen more gradually and arent usually as dramatic