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The Grading of Recommendation, Assessment, Development, and Evaluation (GRADE) tool was used to assess the certainty of the evidence for the two primary biochemical outcomesserum vitamin B12 concentration increase and homocysteine reductionacross all included studies, and separately for randomised controlled trials (RCTs) and observational studies
Maintaining adequate vitamin B12 serum levels may help improve mental health by decreasing the risk of depression and anxiety
stational trophoblastic disease (GTD) GTD stands for Gestational trophoblastic diseases which is a group of rare diseases in which abnormal trophoblast cells grow inside the uterus after conception
Geriatric syndromes in older adults with and without diabetes: a systematic review and meta-analysis
As a co-factor in carboxylase enzymes, Biotin is involved in gluconeogenesis, fatty acid synthesis, and the metabolism of amino acids
Oral, intragastric, and parenteral routes have all shown activity in animal studies
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