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Weight loss of 710% remains the cornerstone of NAFLD treatment according to NICE guidance, with lifestyle modification as first-line intervention

The GLP-1 and dual GLP-1/GIP receptor agonists have emerged as adjuncts to the present gold-standard treatment with CPAP

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Long-term use improves cardiovascular health , reducing the risk of heart attacks and strokes

It works by activating two hormone receptorsGLP-1 and GIPhelping to regulate appetite, increase feelings of fullness, and decrease food intake

9,10,11,12 Deprivation of cysteine by system x c blockage leads to ferroptosis through GSH depletion and lipid peroxidation in some cell contexts, while some types of cells are tolerant to system x c inhibition