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Participants taking the highest weekly dose of retatrutide lost, on average, 28% of their body weight, about 70 pounds, with nearly half losing 30% or more

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acknowledges support from the NIH (R37CA240625, R01CA259111, R01CA298386, P30CA010815 and P30CA047904), the Sandy Rollman Ovarian Cancer Foundation, the American Cancer Society (RSG-19-113-01-CCG), the Congressionally Directed Medical Research Program (HT9425-23-1-0436), the UPMC Hillman Cancer Center and the Wistar Institute