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Drug Interactions Tretinoin may interact with other topical products that cause irritation, such as exfoliants or harsh cleansers

Ingestion of ethanol also affects the gastrointestinal system in a variety of ways

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It helps modulate the immune response, providing support during infections and illnesses

While use is not recommended pregnant women, there is insufficient data on the use of tretinoin or estriol containing creams in nursing mothers