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GLP-1 receptor (GLP-1R) activation Stimulates insulin release and suppresses glucagon secretion Delays gastric emptying Provides central appetite regulation Exhibits biased signaling favoring cAMP over -arrestin recruitment sustained receptor expression and enhanced insulin secretory capacity Benefits include: \Weight Loss: Up to 22.5% reduction in body weight

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For anti-ulcer activity against ethanol-induced stomach mucosal damage, it was diluted in 10% Tween 20 at doses of 62.5, 125, 250, and 500 mg/kg body weight for oral administration as previously described [46]