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This pharmacokinetic profile supports once-weekly subcutaneous administration, delivered via prefilled autoinjector pens available in 0.75 mg, 1.5 mg, 3.0 mg, and 4.5 mg per 0.5 mL dose strengths [54]

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"The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI"