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Researchers wanted to determine whether the effects extended across multiple forms of addiction and whether the drugs could help reduce the most serious consequences associated with substance use disorders

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ETI, West Sussex, UK) by inserting a corn oil-soaked flexible bead probe into the rectum after the intraperitoneal administration of 200 L of vehicle, exendin 939 (50 g/kg), or BCTC 5 mg/kg in wild-type mice ( n = 6)

Valenzuela-Vallejo L, Guatibonza-Garcia V, Mantzoros CS

The mean absolute change at the end of the study at week 52 was significantly greater in the pooled tirzepatide 10 and 15 mg groups than in the insulin degludec group (8.09% vs