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In excess, folic acid can: Increase cancer risk [ R ] Raise homocysteine [ R , R , R ] Cause symptoms of folate deficiency [ R , R , R ] Mask anemia caused by low vitamin B12 [ R ] Increase the risk of having children with autism or allergic diseases like asthma and eczema [ R , R ] Possibly increase the risk of having offspring with insulin resistance and high blood lipids (in rats) [ R ] The general recommendation for folic acid intake is 400 micrograms per day or up to 1700 micrograms per day for pregnant women [ R ]