Like CaMKK2, the PKA signalling pathway is also considered to play a key role in the pathogenesis of bipolar disorder, as increased cyclic AMP levels and PKA activity have been frequently observed in post-mortem brains and peripheral cells of bipolar disorder patients [58,59,60,61]
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This finding was subsequently confirmed in humans, where an increase in exhaled H 2 S gas was observed during intravenous injection of sodium sulfide
Kulik A, Wawer I, Krzywiska E et al (2011) SnRK2 protein kinaseskey regulators of plant response to abiotic stresses
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