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In addition, exendin-4 at 0.1100 nM concentrations for 2496 h increased GLP-1R activation, p53, p21, p38, cAMP, Bax/Bcl-2 ratio, and p38/MAPK activation

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To address this discrepancy, we conducted a matched casecontrol investigation aimed at exploring the potential contributions of plasma TMAO, choline and its related metabolites (namely, TMA, l-carnitine and betaine) to the development of NAFLD among Chinese adults