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Approximately 20,000 particles were selected to generate the initial model in RELION3

Probable predisposition and causes of ME/CFS The diverse symptom presentation and patient heterogeneity indicate that ME/CFS is likely to have a multifactorial origin (23, 30, 53, 58), with multiple physiological processes implicated in the pathogenesis (52, 59)

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10.1111/j.1365-2133.2006.07179.x 111 KangW.YoonK.LeeE