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These GLP-1 agonists include: Trulicity (dulaglutide) Byetta (exenatide) Bydureon (exenatide extended-release) Victoza (liraglutide) Adlyxin (lixisenatide) Ozempic (semaglutide) Rybelsus (semaglutide) The drugs work best for managing glucose levels when combined with diet and exercise

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With long-acting GLP-1 agents, the effect on gastric emptying may diminish somewhat over time, which could reduce reflux symptoms in some patients

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All animals had ad libitum access to food and water and were kept under a standard lightdark cycle