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Extracellular glutathione suppresses human lung fibroblast proliferation

metabolism 45 (6), 591600

C., & Andrade, T

This pathological state creates an imbalance where ROS and RNS production exceeds the neutralizing ability of intrinsic antioxidant systems, thereby establishing conditions of oxidative stress (Rahman and MacNee, 2000)

Serotonin stimulates the 5-HT 3 receptor to release acetylcholine in the nerve ends, which causes smooth muscle contraction and enhanced intestinal secretion ( 3 receptor antagonists which inhibit the 5-HT 3 receptor activation on the mucosal processes of the primary afferent neurons, and reduce activity of the secretory and motor reflex, by inhibiting the submucosal plexus and myenteric plexus respectively (Figure 2)

[DOI] [PMC free article] [PubMed] [Google Scholar] 31.Li Z, Okamoto K-I, Hayashi Y, Sheng M