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SITAgliptin for Depressive Symptoms in Type 2 Diabetes: A Feasibility Randomized Controlled Trial

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Chronic hyperglycemia results in the suppressed activity of mTOR associated with AMP-activated protein kinase-induced increase in ROS formation and enhanced expression of thioredoxin interacting protein (TXNIP) a potential sensor of glucose and oxidative stress (Akpoveso et al

However, for more significant concerns such as melasma, deep hyperpigmentation, or moderate acne scarring, a series of two to three treatments spaced four to six weeks apart is typically recommended for optimal results