Sattar N, Lee MM, Kristensen SL, Branch KR, Del Prato S, Khurmi NS, et al
Without targeted policy interventions, such as expanded insurance coverage or income-based subsidy programs, the benefits of GLP-1 medications may continue to accrue disproportionately to higher-income populations, leaving behind the very communities most affected by obesity
Benedict Jephcote, Editor of Diabetes.co.uk, said: It is encouraging to see that researchers are looking at other ways of stimulating delivery of GLP-1 medication, which has typically been delivered via injection
The mechanism is indirect, primarily driven by rapid weight reduction and nutritional deficiencies rather than direct drug effects
Tiredness may result from reduced caloric intake due to appetite suppression, gastrointestinal side effects limiting food consumption, dehydration from vomiting or diarrhea, changes in blood glucose levels, or metabolic adjustments during significant weight loss
If youre not seeing any of these after four to six weeks, the dose may be too low to achieve therapeutic benefit