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Clinical data shows that 2528% of patients using semaglutide in weight loss trials experienced constipation as a side effect

Yet, these doses would likely be insufficient to impact body composition in such a short period

While the exact mechanisms remain under investigation, several key contributors have been identified

What Wegovy actually does (and doesn't do) Wegovy contains semaglutide, a GLP-1 receptor agonist

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ACS Chem Biol 10:16041609 Dodson M, de la Vega MR, Cholanians AB, Schmidlin CJ, Chapman E, Zhang DD (2019) Modulating nrf2 in disease: timing is everything