At present, there is no published clinical evidence from randomised controlled trials, observational studies, or case series specifically examining the combined use of HGH and retatrutide in human subjects
Hasegawa K, Fujiwara R, Sato K, et al
[Crossref] [PubMed] Hussaini SH, Farrington EA
Novo Nordisk has two other semaglutide drugs, over which it is currently litigating different patents with generics
2.2 Negative Regulation of Ferroptosis by p53 In addition to its ferroptosis-promoting effects, p53 represses ferroptosis by inducing cyclin-dependent kinase inhibitor (CDKN1A, encoding p21), Parkinson disease 2 (PARK2) and iPLA2, or by inhibiting dipeptidyl peptidase-4 (DPP4) (Kang et al., 2019) (Figure 2)
It's not overuse, it's misuse