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Ellis, R

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(2) Preclinicalclinical disconnect: dosing regimens (e.g., colchicine microneedles) lack human PK/PD validation, while transdermal hydrogels need human skin permeability studies to address species-specific stratum corneum variability

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doi: 10.1111/j.1365-2265.1994.tb02486.x 12 BieringHKnappeGGerlHLochsH

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