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Pharmacological agents currently in clinical trials for disorders in neurogastroenterology

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While some peptides like Semaglutide have received FDA approval for specific conditions (such as type 2 diabetes and weight loss), many peptides are prescribed "off-label." This means they are used for purposes beyond their initial FDA-approved use

Unlike prior studies of AMD development that were limited to patients with diabetes, the authors wrote in their paper, their findings suggest that GLP-1 drugs "may be associated with reduced risk even in individuals with obesity but not diabetes, potentially supporting a protective benefit independent of glycemic control and mitigating diabetes as a confounding factor.