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The PRPS1 gene is composed of 7 exons that generate two alternatively spliced mRNAs encoding isoform 1 (318 amino acids) and isoform 2 (114 amino acids)
Gastroenterology 113 , 212218 (1997)
Additionally, a one-pot CRISPR/Cas12a cis-cleavage fluorescent RNA aptamer assay has been developed for the ultrasensitive, label-free detection of miRNA-21 in breast cancer, offering rapid and highly specific diagnostics [108]
Although one study reported a higher level of DAT in the striatum of SHR rats than WKY rats when they were 2-week old [62], overall no significant difference in the levels of D2R or DAT was reported between SHR and WKY rats
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Design, synthesis and bioevaluation of 1,2,4-thiadiazolidine-3,5-dione derivatives as potential GSK-3beta inhibitors for the treatment of Alzheimers disease
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