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Tirzepatide trials (SURMOUNT-1) lasted 72 weeks

[Abstract]2026 Mar:352:151224

Long-chain fatty acids must be esterified to L-carnitine (acylcarnitine) in order to enter the mitochondrial matrix where -oxidation occurs ( Figure 3 )

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Later retracted due to data fabrication concerns involving Kawas and Harding [Benoist et al., 2014 RETRACTED]