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Importantly, proteolytic cleavage of SPARC (secreted protein acidic and rich in cysteine), a matricellular protein abundantly expressed at sites of vascular injury and tissue remodeling, generates GHK-containing fragments that promote endothelial cell proliferation and neovascularization

Its a well-studied copper peptide that has been shown to make a real difference in skin texture and firmness

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They are also capable of transporting and retaining drugs in proximal lymph nodes, maximizing lymphatic drug delivery

Human repeat insult patch tests on foundations containing this ingredient found no sensitization concerns

It's not a magic bullet, but its range of influence in preclinical models is undeniably broad