However, the lack of government oversight of the dietary supplement industry create significant concerns about the purity and content accuracy of these products
A recent report found that this GLP-1 gray market is not only thriving on TikTok, but that TikTok is actually making it easy for users to find the illicit content despite clear violations of TikToks own Community Guidelines The consequences of these unregulated sources are serious: as of July 2025, FDA has received 1,150 adverse event reports related to GLP-1s, including hospitalizations and deaths, while poison control calls specific to GLP-1 usage increased nearly 1,500% between 2019 and 2025, according to data from America's Poison Control Centers
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Chem Commun 49:63136315 Aguilera G, Colin-Gonzalez AL, Rangel-Lopez E, Chavarria A, Santamaria A (2018) Redox signaling, neuroinflammation, and neurodegeneration
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Tirzepatide is a glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for the treatment of type 2 diabetes mellitus and chronic weight management