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(7) Drugs that Reduce Metformin Clearance: May increase risk of lactic acidosis

For the quantitative determination of TMA, the following transitions were considered: m/z 146.1 [M + H]+(of the derivatized TMA) m/z 118.1 as the identifying fragment and m/z 155.1 [M + H]+(of the derivatized D9-TMA) m/z 127.1

Pack extra medication in case a vial gets damaged in transit

Acetyl-L-Carnitine is the acetylated form, studied extensively because the acetyl group changes how the compound is absorbed and used

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SEM Used in Mixed Population (First- or Second-Line Therapy