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Elevated levels of ROS and oxidative damage markers, such as 8-OHdG and MDA, have been detected in the synovial fluid and tissues of RA patients
Effects on beta cells and insulin sensitivity point to a unique clinical profile for this dual agonist
This approach would capitalize both on our understanding of circadian pathophysiological pathways in asthma, and existing redox-targeted therapeutics, whilst minimizing off-target effects associated with hormone based therapies such as melatonin
Warady BA, Pergola PE, Agarwal R, Andreoli S, Appel GB, Bangalore S, et al
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Libraries were quantified with NuQuant, quality checked using a TapeStation instrument (Agilent Technologies) and subjected to 52 bp paired-end sequencing on the NovaSeq 6000 system (Illumina)
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