As lipid hydroperoxides are known for propagating radiation injury, understating the influence of the alteration in expression/activity level of GPx on cellular radiosensitivity has received a lot of attention among researchers
Other recognised adverse effects include: Injection site reactions (redness, itching) Fatigue (uncommon) Dizziness (uncommon) A modest increase in heart rate has been observed Gallbladder disorders , including cholecystitis and cholelithiasis Diabetic retinopathy complications (particularly in patients with pre-existing retinopathy and rapid improvement in glycaemic control) Acute pancreatitis (uncommon) Dysgeusia (taste disturbance) Increases in pancreatic enzymes (amylase/lipase) Serious allergic reactions, though rare, require immediate medical attention
CANVAS), empagliflozin (Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients
Dietary lipids, gut microbiota and lipid metabolism
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Effects on mucin expression, tight-junction protein integrity, gut motility, and inflammatory cytokine profiles have all been characterised
