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10,15,18,23 One trial specifically investigated BD, 11 while another 19 included a small subgroup of nine patients with bipolar depression alongside its primary MDD population
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The STEP program studied semaglutide for weight management ( The New England Journal of Medicine , 2021), while SURMOUNT (NEJM, 2022) and SURMOUNT-OSA (NEJM, 2024) examined tirzepatide for weight and for obstructive sleep apnea
For example, in a small randomised study, people with alcohol use disorder who received low-dose semaglutide not only drank less during a monitored lab session but reported fewer weekly alcohol cravings as well
10.1158/1940-6207.CAPR-13-0058-T
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