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(4) ongoing telehealth follow-up for dose titration and side-effect management

For most patients with stable or treated lymphoproliferative disorders, GLP-1 agonists can be used safely with appropriate monitoring

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Besides the well-known targets such as the inhibition of the mTOR signaling pathway, several additional metformin and phenformin targets (e.g., mGPDH, ATF3, STAT3, GSK3, cyclins) have been identified in other cancers (Thakur et al., 2019)