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Insulin sensitivity improves alongside insulin secretion enhancement

Future moves could widen this coverage difference, significantly weakening the TFL benefit

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What the future holds: ongoing and upcoming research The non-weight-loss benefits of tirzepatide are still being actively investigated

The brain, after the pancreas, contains the highest density of GLP-1 receptors helping explain GLP-1s impact on appetite regulation and satiety (see Figure 1)

In the sections below, we will explore employer adoption rates for GLP-1 coverage, the immense pressure on PMPM costs, and the specific strategies companies are using to manage this new expense