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Administration of LBI to house dust mite-stimulated human peripheral blood mononuclear cells (PBMCs) increases interferon- (IFN-) production, resulting in decreased interleukin (IL)-4 and IgE levels 8,9

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521,522,523 In addition, macrophages exacerbate the inflammatory response by promoting the secretion of ROS, cytokines, and chemokines

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Nutrients 2021;13:942

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Clinical trials in dogs are limited

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