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These studies showed that one-third of a subset of classical EDS patients that could be evaluated (because they are heterozygous for polymorphisms of COL5A1 ) did not express the mutant allele

In 2025, biosimilars held approximately 20 percent average market share of the total biologics market in the US, up from less than 5 percent in 2020

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Two very different populations, however the approach to helping both groups is actually very similar