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133 In human trials, the prebiotic fibers inulin and dextrin induced reductions in serum levels of total cholesterol (-9% and -2% for inulin and dextrin, respectively), LDL cholesterol (-1 % for dextrin), and triglycerides (-21% for inulin)

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Studies with congenitally leptin-deficient, severely obese subjects revealed that administration of physiological doses of leptin decreased food intake and body weight (7)

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