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Peptides act differently in isolation than in combination

Mechanism of Action

These include different GLP-1/GIP combinations with varying receptor affinity profiles, triple agonists that add glucagon activity, and oral formulations of dual agonists

1 Improved Blood Glucose Control: GLP-1 agonists can reduce HbA1c (a marker of average blood glucose levels over 3 months) by around 1% to 2%, which is comparable to or even exceeds other diabetes treatments

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Retatrutide is a GLP-1 drug, in the same family as Ozempic (semaglutide) and Mounjaro (tirzepatide)